40th International JVE Conference on Dynamics of Biological Systems
September 26-28, 2019 in Kaunas, Lithuania
Topics of the Conference:
- ▸ Medical Devices, Materials, Measurement and Instrumentation
- ▸ Health Care Technology (topics related to dynamics and oscillatory evolution)
- ▸ Medical Image and Signal Processing (topics related to dynamics, oscillations, wave propagation)
- ▸ Modelling, Simulation and Control (topics related to biomedical engineering)
- ▸ Biomechanics
Major conference topic: "Biomedical Engineering of Dynamical Systems"
40th International JVE Conference on Dynamics of Biological Systems is an integral part of Vibroengineering Series Conferences and will be held in Kaunas, Lithuania. Internationally renowned invited speakers and contributing authors from all over the world will present the latest advances in the field of Biomedical Engineering of Dynamical Systems. This conference will feature a broad range of high-level technical presentations including invited distinguished experts.
The conference will provide an opportunity to communicate your recent research advances, exchange ideas in innovative Biomedical Engineering technologies, meet old friends and make new business partners in Biomedical Engineering. With your participation, this Conference will be an exciting scientific event, a fruitful opportunity to promote scientific research and technological development of Biomedical Engineering and its applications.
The conference is organized by JVE International with the partnership of Lithuanian University of Health Sciences, Kaunas University of Technology, Vytautas Magnus University, Vienna University of Technology (Austria), Silesian University of Technology (Poland), Hohai University (China), Barcelona University (Spain) and HeartMath Institute (USA).
Keynote Speakers

Physiological Coherence: Bridging Personal, Social and Global Synchronization

Innovative clinical medicine using auricular vagus nerve stimulation
Fast track surgery and the surgical approach to heal chronic wounds - even with the indication for amputation - are examples in which the auricular vagus nerve stimulation plays a crucial role. Basic knowledge about the effects of the auricular vagus stimulation and the associated clinical studies will be presented.

New approaches in medicine: Endobiogeny-integrative physiology and systems analysis in the clinic
Endobiogeny is a theory of complex global systems analysis and integrative physiology. It was developed by physicians to assist medical decision making. Serum biomarkers are considered to be the downstream output of global upstream neuroendocrine regulators of metabolism. They are related through a combinatorial process, then algorithmically analyzed. This approach allows for a dynamic, integrated, interrelated and holographic approach to the human being at multiple scales of function. At microscopic biological scale, cellular processes can be evaluated. At the mesoscopic physiologic scale, tissue, organ and global organismic function can be evaluated. At the macroscopic phenomenological scale, psychological, social, and symbiotic tendencies, and, response to chronobiologic, geomagnetic and cosmobiologic demands can be evaluated. The system offers clinicians the ability to observe the evolution on the patient in response to interventions across space and time. This offers a new approach to precision and personalized medicine based on the organism’s expressed phenotypic capabilities for auto-regulation, rather than latent genetic possibilities.

Multimodal in vivo imaging in preclinical evaluation of medical interventions in stroke (and its context in the digital society)
The critical step in the preclinical evaluation of envisaged medical interventions (new drugs, stem cell applications, electroceuticals) is testing them on
the laboratory animals. In case of the ischemic stroke, a clinically relevant animal model is middle cerebral artery occlusion (MCAO). Due to the complex
cascade of events after brain ischemia, longitudinal follow up of stroke consequences is a crucial element, and it is enabled through assessing the
morphological and molecular parameters by the in vivo imaging.
In our research, we use magnetic resonance imaging (7T Bruker MRI) and bioluminescence imaging (optical imager Perkin Elmer IVIS Spectrum) to follow
up the animals up to 28 days after ischemic brain lesion. The dedicated collection of transgenic animals carrying luciferase reporters enables to get
insight in neuroinflammation (Tlr2-luc/GFP transgenic mouse), axonal repair (Gap43-luc/GFP transgenic mouse), and apoptosis (caged-luciferin bioluminescence
imaging). Each modality is informative individually, but we could show that using multimodal approach and standardizing the bioluminescence according to
the MRI measurements enhances the detection of the significant changes among tested animal groups. In case of mice with Tlr2-deficiency, which exhibits
modified neuroinflammation after ischemic lesion, the in vivo imaging revealed the enhanced elements of brain repair but as well prolonged and increased
apoptosis.
The stroke, being a major health problem, is in need to be addressed through innovative approaches in order to help the patients and protect the
healthy ones. The digital society being global and immediate generates both benefits and risks for the individuals expecting to be treated and cured
by current advances of medical technologies. I would argue that translating the logic of the offline environment can create the confusion and impasses
in the online context. The complexity of the digital geometries distort online space and time, having as a consequence disruption of the medical
regulations and the risky individual trajectories in a search for health. The navigation through digital knowledge landscapes appears to be a key
element of the person-centered health care.

Effects of complex movements on the brain as a result of increased decision-making

Development of intravascular stent robot with cross type receiver
This study proposes a stent motor as a medical device. A stent is a medical instrument inserted in a constricted part of a blood vessel to expand the blood vessel. However, the problem is that plaque accumulates around the installed stent and causes the blood vessel to narrow again. A stent motor is used to remove plaque. A stent motor consists of a receiver part to receive ultrasonic vibration and a stator part to drive the motor in the blood vessel. The purpose of this study was to develop a stent motor and determine its optimum design. It was possible to drive a stent motor by subjecting a disk-shaped receiver to strong ultrasonic vibrations. Experiments were performed on the stent motor with several types of receivers by changing their size and shape, and the efficiency was evaluated. Correlation between the design of the stent motor, such as the number of turns in the stator and the shape of the receiver, and the rotational speed was clarified.
Personal Health Devices for Unobtrusive Monitoring of Chronic Diseases
The aging population is causing a significant increase in the prevalence of chronic diseases such as chronic kidney disease, atrial fibrillation, peripheral arterial disease, etc. Epidemiological studies have estimated 13 % of chronic kidney disease prevalence all over the world, 2% of atrial fibrillation and 20% of peripheral arterial disease in the population over 70 years of age. Often chronic diseases exist in parallel and make matters worse by putting a patient in comorbidity or multimorbidity state. Vicious cycles involving multiple organs and physiological systems, e.g., cardio-renal syndrome, are especially dangerous for a patient. It is hypothesized that continuous physiological monitoring, early diagnostics, and intervention could help to break such cycles. However, the monitoring technology must be unobtrusive to the patient; otherwise, the patient compliance will be low. To this end, researchers of the Biomedical Engineering Institute, Kaunas University of Technology, developed two types of unobtrusive personal health devices intended to be used at home: a wrist-worn multisensory device for continuous health monitoring and a multiparametric weighing scale for intermittent monitoring. The tools are used in several projects with clinical partners. The wrist-worn multisensory device is under testing in two projects related to arrhythmia (atrial fibrillation) monitoring after myocardial infarction and brain stroke. The multiparametric weighing scale is intended to be used by chronic kidney disease patients at home to prevent complications. The results of these studies will be presented.
The Brain as a Dynamic System: A bottom-up perspective on cognitive processes underlying food intake regulation
Maintenance of energy homeostasis, i.e. the balance between caloric intake and energy expenditure, has to be maintained in a tight range
to ensure health and survival. Throughout evolution, a sophisticated neuronal network has developed that integrate various streams of
information from the body about energy availability. This network enables us to adapt a wide range of behavioral and autonomic responses
to precisely control food intake, energy expenditure, and substrate flux across different peripheral organs. Dysregulation of the underlying
homeostatic circuits causes prevalent diseases, such as obesity and type-2 diabetes mellitus, which are on an epidemic rise in industrialized societies.
At the example of regulation of food intake behavior, I discuss how the brain processes external sensory and internal homeostatic signals
to initiate –dynamically– behavioral and physiological responses. Here, a focus will be on circuit-level models of metabolic mechanisms.
In this regard, emphasis will be on those biological pathways that mediate individual differences in behavior and risk for (psycho-)pathology
implicated in the control of body weight and energy homeostasis. Accordingly, I explore the role of reward processing and motivated behavior
in obesity and related disorders.
Principal topic of the conference is Biomedical Engineering of Dynamical Systems and other topics are also included in the conference agenda.
Medical Devices, Materials, Measurement and Instrumentation
- Bioinstrumentation
- Biosensors and Transducers
- Measurement and Instrumentation
- Micro-technology, BioMEMS, Lab-on-Chip
- Robotics in Medicine
- Ethical implications of biotechnology and bioengineering
Health Care Technology (topics related to dynamics and oscillatory evolution)
- Biomedical applications of Electromagnetic Fields
- Complexity in Health Sciences
- Medical Physics and Physiology
- Therapeutic Engineering (electrotherapy, implant technology, etc.)
Medical Image and Signal Processing (topics related to dynamics, oscillations, wave propagation)
- Biocomputing and Bioinformatics
- Biomedical Signal Processing
- Big Data (Analysis, Representation and Visualization)
- ECG, EEG, EMG Analysis
- Optical and Ultrasound Imaging
Modelling, Simulation and Control (topics related to biomedical engineering)
- Biomathematics
- Biomedical Computing
- Simulation in Biomedicine, Sports and Ergonomics
- Control of Complex Processes in Biology
Biomechanics
- Bone and Joint Engineering
- Musculoskeletal Modelling and Tissue Mechanics
- Physiotherapy and Sports Biomechanics
- Prosthetics and Orthotics
All papers presented at International JVE Conference will be published as short Conference papers in Vibroengineering Procedia. Conference papers published in Vibroengineering Procedia is indexed in Scopus, EI Compendex, Inspec, Gale Cengage, Google Scholar and EBSCO.
Authors of papers presented at International JVE Conferences are invited to extend their manuscripts to full journal papers which will be considered for publication in one of our Open Access journals:
- Journal of Complexity in Health Sciences (indexed in DOAJ, Google Scholar, CNKI, CrossRef)
- Journal of Vibroengineering (indexed in ESCI, Clarivate Analytics, Compendex, Inspec, Publons, Scopus, DOAJ, Ebsco, Gale, CNKI, Google Scholar, CrossRef)
- Journal of Measurements in Engineering (indexed in ESCI, Clarivate Analytics, Inspec, EBSCO, Gale, Ebsco, CNKI, Google Scholar, CrossRef)
- Mathematical Models in Engineering (indexed in Ebsco, Gale, CNKI, Google Scholar, CrossRef)
Organizing Committee

TU Wien, Faculty of Electrical Engineering and Information Technology, Austria
Chair of the Conference

Kaunas University of Technology, JVE International, Lithuania
Chair of the Conference

Prof. Alfonsas Vainoras
Lithuanian University of Health Sciences, Lithuania
Chair of the Conference
Local Organizing Committee Members
International Organizing Committee Members
Organizing Committee Members
Sponsors and Partners
Conference in Kaunas, Lithuania is organized by JVE International in partnership with Lithuanian University of Health Sciences, Kaunas University of Technology, Vytautas Magnus University, Vienna University of Technology (Austria), Silesian University of Technology (Poland), Hohai University (China), Barcelona University (Spain) and HeartMath Institute (USA).
For more information, inquiries, sponsorship requests or any other co-operation interests, please Contact Us
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